cystic fibrosis (CF)

cystic fibrosis (CF)

Inherited metabolic disorder characterized by production of thick, sticky mucus.

It is recessive (see recessiveness) and the most common inherited disorder (about 1 per 2,000 live births) in those of European ancestry. Concentrated mucous secretions in the lungs plug the bronchi, making breathing difficult, promoting infections, and producing chronic cough, recurrent pneumonia, and progressive loss of lung function, the usual cause of death. The secretions interfere with digestive enzymes and block nutrient absorption. Abnormally salty sweat is the basis for diagnosis of cystic fibrosis. Treatment includes enzyme supplements, a diet high in calories, protein, and fat, vigorous physical therapy, and antibiotics. Persons with cystic fibrosis once seldom survived beyond childhood; now more than half reach adulthood, though males are usually sterile.

* * *


Universalium. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Cystic fibrosis — Classification and external resources A breathing treatment for cystic fibrosis, using a mask nebuliser and a ThAIRapy Vest ICD 10 E …   Wikipedia

  • cystic fibrosis — n. a congenital disease, usually of children, characterized by fibrosis and malfunctioning of the pancreas, and by frequent respiratory infections …   English World dictionary

  • cystic fibrosis — cystic fibrosis. См. муковисцидоз. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • cystic fibrosis — ► NOUN ▪ a hereditary disorder which affects the exocrine glands, resulting in the production of abnormally thick mucus and leading to the blockage of the pancreatic ducts, intestines, and bronchi …   English terms dictionary

  • cystic fibrosis — Pathol. a hereditary chronic disease of the exocrine glands, characterized by the production of viscid mucus that obstructs the pancreatic ducts and bronchi, leading to infection and fibrosis. [1950 55] * * * ▪ pathology also called… …   Universalium

  • Cystic fibrosis — One of the most common grave genetic (inherited) diseases, CF affects the exocrine glands and is characterized by the production of abnormal secretions, leading to mucous build up. This accumulation of mucus can impair the pancreas and,… …   Medical dictionary

  • cystic fibrosis — [[t]sɪ̱stɪk faɪbro͟ʊsɪs[/t]] N UNCOUNT Cystic fibrosis is a serious disease of the glands which usually affects children and can make breathing difficult …   English dictionary

  • cystic fibrosis — fibrocystic disease of the pancreas; = mucoviscidosis a hereditary disease affecting cells of the exocrine glands (including mucus secreting glands, sweat glands, and others). The faulty gene responsible for the most common form of the disease… …   The new mediacal dictionary

  • Cystic fibrosis transmembrane conductance regulator — (ATP binding cassette sub family C, member 7) NBD1 of human CFTR complexed with ATP. PDB rendering based on 1xmi …   Wikipedia

  • Cystic Fibrosis Canada — Type Health Charity Registration No. 10684 5100 RR0001 Founded 15 July 1960 ( …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”