Bordet, Jules (-Jean-Baptiste–Vincent)

Bordet, Jules (-Jean-Baptiste–Vincent)
born June 13, 1870, Soignies, Belg.
died April 6, 1961, Brussels

Belgian bacteriologist and immunologist.

In 1895 he found that two blood serum components cause bacteriolysis (bacterial cell-wall rupture), one a heat-stable antibody in animals immune to the bacterium and the other a heat-sensitive complement in all animals. In 1898 he discovered hemolysis (rupture of foreign erythrocytes), a similar process that also requires complement. This research was vital to the foundation of serology, the study of immune reactions in body fluids. His work with Octave Gengou led to serological tests for many diseases, including typhoid, tuberculosis, and syphilis (the Wassermann test). In 1906 they discovered Bordetella pertussis, which causes whooping cough. In 1919 Bordet received a Nobel Prize.

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