complement-fixation test

complement-fixation test
/kom"pleuh meuhnt fik say"sheuhn/, Med.
a test for diagnosing an infectious disease by detecting the presence of antibody in the blood, based on the fixing of a known quantity of complement to the antigen being tested and the specific antibody that combines with it. Abbr.: CFT
[1910-15]

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Universalium. 2010.

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  • complement-fixation test — n a diagnostic test for the presence of a particular antibody in the serum of a patient that involves inactivation of the complement in the serum, addition of measured amounts of the antigen for which the antibody is specific and of foreign… …   Medical dictionary

  • complement-fixation test — noun : a test for the presence of a particular antibody made by addition of complement and an indicator system to a mixture of known antigen and a serum suspected to contain the specific antibody for this antigen and used especially in the… …   Useful english dictionary

  • complement fixation test — noun a blood test in which a sample of serum is exposed to a particular antigen and complement in order to determine whether or not antibodies to that particular antigen are present; used as a diagnostic test • Hypernyms: ↑blood test • Hyponyms:… …   Useful english dictionary

  • complement fixation test — see under fixation …   Medical dictionary

  • complement fixation — n the process of binding serum complement to the product formed by the union of an antibody and the antigen for which it is specific that occurs when complement is added to a mixture (in proper proportion) of such an antibody and antigen * * *… …   Medical dictionary

  • complement fixation — the binding of complement to the complex that is formed when an antibody reacts with a specific antigen. Because complement is taken up from the serum only when such a reaction has occurred, testing for the presence of complement after mixing a… …   The new mediacal dictionary

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  • test — 1. To prove; to try a substance; to determine the chemical nature of a substance by means of reagents. 2. A method of examination, as to determine the presence or absence of a definite disease or of some substance in any of the fluids, tissues,… …   Medical dictionary

  • Coombs test — Diagnostics MeSH D003298 Coombs test (also known as Coombs test, antiglobulin test or AGT) refers to two clinical blood tests used in immunohematology and immunology. The t …   Wikipedia

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