colchicine

colchicine
/kol"cheuh seen', -sin, kol"keuh-/, n. Pharm.
a pale yellow, crystalline alkaloid, C22H25NO6, the active principle of colchicum.
[1850-55; COLCHIC(UM) + -INE2]

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      drug used in the treatment of gout, a disease that is characterized by severe inflammation in one or more of the joints of the extremities. Colchicine is obtained from the autumn crocus (Colchicum autumnale). The mechanism by which colchicine relieves the pain of gout, which is caused by solid deposits of uric acid in the joints, the kidneys, and other tissues, is unknown. Side effects include diarrhea and other gastrointestinal disturbances.

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  • Colchicine — Systematic (IUPAC) name N ​[(7S …   Wikipedia

  • Colchicine — Structure chimique Général Nom IUPAC N [(7S) 5,6,7,9 tétrahydro 1,2,3,10 tétraméthoxy 9 oxobenzo[a]heptalen 7 yl)acé …   Wikipédia en Français

  • colchicine — [ kɔlʃisin ] n. f. • 1834; de colchique ♦ Pharm. Alcaloïde toxique extrait des graines de colchique, antimitotique, employé à faible dose dans le traitement de la goutte. ● colchicine nom féminin Substance d origine végétale possédant des… …   Encyclopédie Universelle

  • Colchicine — Col chi*cine (? or ?), n. [Cf. F. colchicine.] (Chem.) A powerful vegetable alkaloid, {C17H19NO5}, extracted from the {Colchicum autumnale}, or meadow saffron, as a white or yellowish amorphous powder, with a harsh, bitter taste; called also… …   The Collaborative International Dictionary of English

  • colchicine — colchicine. См. колхицин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • colchicine — [käl′chi sēn΄, käl′chisin΄; käl′kisēn΄, käl′kisin΄] n. [< COLCHICUM + INE3] a poisonous, yellow alkaloid, C22H25NO6, extracted from the seeds or corms of a species of colchicum ( Colchicum autumnale): used in the treatment of gout, in genetic… …   English World dictionary

  • Colchicine — A substance found in a plant that is used in clinical medicine for the treatment of gouty arthritis and in the laboratory to arrest cells during cell division (by disrupting the spindle) so their chromosomes can be visualized. The name colchicine …   Medical dictionary

  • colchicine — kolchicinas statusas T sritis augalininkystė apibrėžtis Nuodingas augalinės kilmės alkaloidas, sukeliantis poliploidizaciją dėl mitozės achromatinės verpstės suardymo. atitikmenys: angl. colchicine rus. колхицин …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • colchicine bath method — colchicine bath method. См. метод колхициновых ванн. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • colchicine — noun Date: circa 1847 a poisonous alkaloid C22H25NO6 that inhibits mitosis, is extracted from the corms or seeds of the autumn crocus (Colchicum autumnale), and is used especially in the treatment of gout and to produce polyploidy in plants …   New Collegiate Dictionary

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