chloroquine

chloroquine
/klawr"euh kwin, -kween', klohr"-/, n. Pharm.
a synthetic substance, C18H26ClN3, used chiefly to control malaria attacks.
[1945-50; CHLORO-2 + QUIN(OLIN)E]

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▪ drug
      synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas (amoeba). Some mild side effects may occur, including headache and abdominal cramps, which are common to antimalarials. Visual impairment may occur with long-term use of chloroquine.

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Universalium. 2010.

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Look at other dictionaries:

  • Chloroquine — Systematic (IUPAC) name N (7 chloroquinolin 4 yl) N,N diethyl pentane 1,4 diamine Clinical data Trade names …   Wikipedia

  • Chloroquine — Général Nom IUPAC N (7 chloroquinolin 4 yl) N,N diethyl pentane 1,4 diamine …   Wikipédia en Français

  • chloroquine — [ klɔrɔkin ] n. f. • 1953; en angl. 1946; de chloro et quin(oléine) ♦ Méd. Médicament synthétique employé dans le traitement du paludisme et de certaines arthrites. Syn. (déposé) NIVAQUINEn. f. ● chloroquine nom féminin Dérivé chloré de la… …   Encyclopédie Universelle

  • chloroquine — [klôr′ə kwin] n. [< CHLORO + QUIN(OLIN)E] a synthetic drug, C18H26ClN3, used in treating malaria, certain kinds of arthritis, etc …   English World dictionary

  • chloroquine hydrochloride — the dihydrochloride salt of chloroquine, used for suppression and treatment of malaria and as a second line agent for treatment of extraintestinal amebiasis; administered intramuscularly …   Medical dictionary

  • chloroquine phosphate — [USP] the phosphate salt of chloroquine, used for suppression and treatment of malaria, for treatment of extraintestinal amebiasis, and as a lupus erythematosus suppressant; administered orally …   Medical dictionary

  • chloroquine-resistant malaria — /ˌklɔroʊkwin rəzɪstənt məˈlɛəriə/ (say .klawrohkween ruhzistuhnt muh lairreeuh) noun the most severe form of malaria, caused by the microorganism Plasmodium falciparum, which can no longer be controlled by the use of the drug chloroquine. Also,… …  

  • chloroquine — noun Etymology: chlor + quinoline Date: 1946 an antimalarial drug C18H26ClN3 administered in the form of its bitter crystalline diphosphate …   New Collegiate Dictionary

  • chloroquine — Antimalarial drug that has the interesting property of increasing the pH within the lysosomewhen added to intact cells in culture …   Dictionary of molecular biology

  • chloroquine — noun A 4 aminoquinoline drug used to treat and prevent malaria, having the chemical formula CHClN …   Wiktionary

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