acetanilide

acetanilide
/as'i tan"l uyd'/, n. Chem., Pharm.
a white, crystalline, odorless, organic powder, C8H9NO, produced by the action of glacial acetic acid on aniline, used chiefly in organic synthesis and formerly in the treatment of fever and headache.
Also, acetanilid /as'i tan"l id/. Also called acetylaniline.
[1860-65; ACET- + ANILIDE]

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▪ drug
      synthetic organic compound introduced in therapy in 1886 as a fever-reducing drug. Its effectiveness in relieving pain was discovered soon thereafter, and it was used as an alternative to aspirin for many years in treating such common complaints as headache, menstrual cramps, and rheumatism. Excessive or prolonged use engenders toxic side effects: it interferes with the function of hemoglobin, the oxygen-carrying pigment of the blood. In the body acetanilide is mostly converted to acetaminophen, which has replaced acetanilide in therapy because it is less likely to induce blood disorders.

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Universalium. 2010.

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  • acétanilide — ⇒ACÉTANILIDE, subst. masc. CHIM. Composé organique, amide, solide blanc, de formule C6H6NHCOCH3, dérivé de l aniline et obtenu par action du chlorure d acétyle sur l aniline : • 1. C est à cette réaction que l on doit attribuer l origine de l… …   Encyclopédie Universelle

  • Acetanilide — Ac et*an i*lide, n. [Acetyl + anilide.] (Med.) An amide formed from aniline and an acetyl group ({C6H5.NH.CO.CH3}); it is a white crystalline compound used as an analgesic and also as an antipyretic. It has molecular weight 135.16. Syn:… …   The Collaborative International Dictionary of English

  • acetanilide — [as΄ət an′ə līd΄] n. [ ACET(O) + ANIL(INE) + IDE] a white, crystalline organic substance, C6H5NHCOCH3, produced by the action of acetic acid on aniline: it is used as a drug to lessen pain and fever, in making dyes, etc …   English World dictionary

  • acetanilide — acetanilidas statusas T sritis chemija formulė CH₃CONHC₆H₅ atitikmenys: angl. acetanilide rus. ацетанилид ryšiai: sinonimas – N feniletanamidas …   Chemijos terminų aiškinamasis žodynas

  • acetanilide — or acetanilid noun Etymology: International Scientific Vocabulary Date: circa 1864 a white crystalline compound C8H9NO that is derived from aniline and acetic acid and is used especially to relieve pain or fever …   New Collegiate Dictionary

  • acetanilide — noun The amide derived from acetic acid and aniline; once used medicinally as an analgesic and antipyretic. Syn: antifebrine …   Wiktionary

  • acetanilide — ac·et·an·i·lide or ac·et·an·i·lid .as ə tan əl .īd, əl əd n a white crystalline compound C8H9NO that is derived from aniline and acetic acid and is used esp. to relieve pain or fever called also phenylacetamide …   Medical dictionary

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