Flourens, Marie-Jean-Pierre

▪ French physiologist

born , April 15, 1794, Maureilhan, France

died Dec. 6, 1867, Montgeron

      French physiologist who was the first to demonstrate experimentally the general functions of the major portions of the vertebrate brain.

      After receiving his medical degree from the University of Montpellier, Flourens went to Paris, where the renowned French naturalist Georges Cuvier (Cuvier, Georges, Baron) became his patron. Under his sponsorship, Flourens conducted a series of experiments (1814–22) to determine physiological changes in pigeons after removal of certain portions of their brains (brain). He found that removal of the cerebral hemispheres, at the front of the brain, destroys will, judgment, and all the senses of perception; that removal of the cerebellum, at the base of the brain, destroys the animal's muscular coordination and its sense of equilibrium; and that removal of the medulla oblongata, at the back of the brain, results in death. These experiments led him to conclude that the cerebral hemispheres are responsible for higher psychic and intellectual abilities, that the cerebellum regulates all movements, and that the medulla controls vital functions, especially respiration. Flourens was also the first to recognize the role of the semicircular canals of the inner ear in maintaining body equilibrium and coordination.

      Flourens became professor of comparative anatomy at the museum of the Jardin des Plantes in 1832 and professor at the Collège de France in 1855. He summarized his brain studies in Recherches expérimentales sur les propriétés et les fonctions du système nerveux dans les animaux vertébrés (1824; “Experimental Researches on the Properties and Functions of the Nervous System in Vertebrate Animals”).

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