theophylline

theophylline
/thee'euh fil"een, -in/, n. Pharm.
a white, crystalline, poisonous alkaloid, C7H8N4O2, an isomer of theobromine, extracted from tea leaves or produced synthetically: used to relieve bronchial spasms, in the treatment of certain heart conditions, and as a diuretic.
[1890-95; theo-, irreg. comb. form repr. NL thea tea + -PHYLL + -INE2]

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drug
      alkaloidal drug used in medicine as an antiasthmatic, coronary vasodilator, and diuretic. Theophylline is a xanthine alkaloid, a methylxanthine chemically related to caffeine and theobromine. Along with caffeine, it is an active constituent of tea (Camellia sinensis), but it is commercially produced in pharmaceutical manufacture by chemical synthesis.

      Administered orally or rectally in the treatment of asthma, it facilitates breathing by relaxing the bronchioles in the lungs. It is administered by injection for the treatment of congestive heart failure to stimulate the heart and increase the total output of blood by the heart. Given orally, it acts as a diuretic by inhibiting reabsorption in the renal (kidney) tubules.

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Universalium. 2010.

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  • theophylline — An alkaloid found with caffeine in tea leaves (commercial t. is prepared synthetically); a smooth muscle relaxant, diuretic, cardiac stimulant, and vasodilator; used in bronchial asthma and other forms of chronic obstructive …   Medical dictionary

  • theophylline — n. an alkaloid, occurring in the leaves of the tea plant, that has a diuretic effect and relaxes smooth muscle, especially of the bronchi (it is an antimuscarinic drug). Theophylline preparations, particularly aminophylline, are used mainly as… …   The new mediacal dictionary

  • theophylline — teofilinas statusas T sritis chemija apibrėžtis alkaloidas formulė (CH₃)₂(O=)₂C₅H₂N₄ atitikmenys: angl. theophylline rus. теофиллин ryšiai: sinonimas – 1,3 dimetil 2,6 purindionas …   Chemijos terminų aiškinamasis žodynas

  • theophylline — noun Etymology: International Scientific Vocabulary theo (from New Latin thea tea) + phyll + 2 ine Date: circa 1894 a feebly basic bitter crystalline compound C7H8N4O2 present in tea leaves that is isomeric with theobromine and is used in… …   New Collegiate Dictionary

  • theophylline — (= 1,3 dimethylxanthine) Inhibits cAMP phosphodiesterase, and is often used in conjunction with exogenous dibutyryl cyclic AMP to raise cellular cAMP levels. Other, less potent, methylxanthines are caffeine, theobromine and aminophylline …   Dictionary of molecular biology

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