reserpine

reserpine
/res"euhr pin, -peen', reuh serr"pin, -peen/, n. Pharm.
an alkaloid, C33H40N2O9, obtained from the root of the rauwolfia, Rauwolfia serpentina, used in the treatment of hypertension.
[1950-55; < G Reserpin, equiv. to reserp- (prob. irreg. < NL Rauwolfia serpentina (Rauwolfia RAUWOLFIA + LL serpentina, fem. of serpentinus SERPENTINE)) + G -in -INE2]

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▪ drug
      drug derived from the roots of certain species of the tropical plant Rauwolfia (Rauvolfia). The powdered whole root of the Indian shrub Rauwolfia serpentina historically had been used to treat snakebites, insomnia, hypertension (high blood pressure), and insanity. Reserpine, isolated in 1952, was the first of many Rauwolfia alkaloids found in the crude drug. Because the drug produces a profound and prolonged tranquilizing action, it was once used in treating schizophrenia. Reserpine is sometimes used in treating hypertension, though newer antihypertensive drugs with fewer central nervous system side effects are the preferred treatment.

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Universalium. 2010.

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  • reserpine — [ri sʉr′pin, ri sʉr′pēn; res′ər pēn΄] n. [Ger reserpin, prob. arbitrary contr. < ModL Rauwolfia serpentina + Ger in, INE3] a crystalline alkaloid, C33H40N2O9, extracted from the root of various rauwolfias (esp. Rauwolfia serpentina), used in… …   English World dictionary

  • Reserpine, an Early Psychiatry Drug —    (from 1954)    Although Ayurvedic practitioners in India had used the roots of the Rauwolfia plant for centuries in the treatment of mental illness, it was only in the early 1950s that the drug became part of the revolution in… …   Historical dictionary of Psychiatry

  • reserpine — noun Etymology: German Reserpin, probably irregular from New Latin Rauwolfia serpentina, a species of rauwolfia Date: 1952 an alkaloid C33H40N2O9 extracted especially from the root of rauwolfias and used as a tranquilizer especially in psychotic… …   New Collegiate Dictionary

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  • reserpine — An ester alkaloid isolated from the root of certain species of Rauwolfia; it decreases the 5 hydroxytryptamine and catecholamine concentrations in the central nervous system and in peripheral tissues; used in conjunction with other hypotensive… …   Medical dictionary

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