quinidine

quinidine
/kwin"i deen', -din/, n. Pharm.
a colorless, crystalline alkaloid, C20H24N2O2, isomeric with quinine, obtained from the bark of certain species of cinchona trees or shrubs, used chiefly to regulate heart rhythm and to treat malaria.
[1830-40; QUIN(INE) + -ID3 + -INE2]

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▪ drug
      drug used in the treatment of abnormal heart rhythms ( arrhythmia) and malaria. Obtained from the bark of the Cinchona tree, quinidine shares many of the pharmacological actions of quinine; i.e., both have antimalarial and fever-reducing activity. The main use of quinidine, however, involves its activity as a myocardial depressant—that is, it depresses the excitability and conduction velocity of nerve impulses and the contractility of the heart muscle. The drug also tends to lower blood pressure. Nausea, vomiting, diarrhea, and skin rash are common reactions to the use of quinidine.

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Universalium. 2010.

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  • quinidine — [kwin′ə dēn΄, kwin′idin] n. [< quina (see QUININE) + ID + INE3] a colorless, crystalline alkaloid, C20H24N2O2, isomeric with and resembling quinine, extracted from cinchona bark …   English World dictionary

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  • quinidine gluconate — [USP] the gluconate salt of quinidine, having the same actions as the base; used in the treatment of certain cardiac arrhythmias, administered orally or intravenously, and in the treatment of life threatening falciparum malaria, administered… …   Medical dictionary

  • quinidine polygalacturonate — a salt of quinidine, having the same actions and uses as the base; administered orally in the treatment of certain cardiac arrhythmias …   Medical dictionary

  • quinidine sulfate — [USP] the sulfate salt of quinidine, having the same actions and uses as the base; administered orally in the treatment of certain cardiac arrhythmias …   Medical dictionary

  • quinidine — noun Etymology: International Scientific Vocabulary, from quinine Date: 1836 an alkaloid C20H24N2O2 that is stereoisomeric with quinine and is used in the form of its sulfate or gluconate to treat cardiac rhythm irregularities …   New Collegiate Dictionary

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