/nuy"euh sin/, n. Biochem.
[1935-40; NI(COTINIC) AC(ID) + -IN2]

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Water-soluble vitamin of the vitamin B complex, essential to growth and health in animals, including humans.

It is found in the body only in combined form as a coenzyme, nicotinamide adenine dinucleotide (NAD), which is involved in the metabolism of carbohydrates and the oxidation of sugar derivatives and other substances. One of the most stable vitamins, it survives most cooking and most preserving processes. It is widely found in dietary sources, especially lean meat. Deficiency causes pellagra. It is used as a drug to reduce high cholesterol levels in the blood.

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also called  nicotinic acid  and  vitamin B3 

      water-soluble vitamin of the B complex. It is also called the pellagra-preventive (pellagra) vitamin because an adequate amount in the diet prevents pellagra, a chronic disease characterized by skin lesions, gastrointestinal disturbance, and nervous symptoms. Niacin is interchangeable in metabolism with its amide, niacinamide (nicotinamide). Like the vitamins thiamin (vitamin B1) and riboflavin (vitamin B2), niacin functions as part of a coenzyme involved in the metabolism of carbohydrates and acts to catalyze the oxidation of sugar derivatives and other substances. It has the following chemical structure:

      Niacin, which was identified as a pellagra preventive in 1937, is widely distributed among plants and animals. Lean meat is generally a good source. Approximately 15 mg per day (1 mg = 0.001 gram) of nicotinic acid is required by humans. In the intestinal tract, the amino acid tryptophan can be converted to niacin by bacterial action and thus can serve as a source for part of the required niacin. This explains scientists' early observation that the protein in such foods as eggs and milk, both poor sources of niacin, can nevertheless prevent or cure pellagra.

      Niacin is one of the most stable vitamins, resisting most cooking and preserving processes. Apart from its value as a vitamin, niacin is used in small daily doses to reduce high cholesterol levels in the blood.

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Universalium. 2010.

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  • niacin — iacin n. A B vitamin (vitamin B5) essential for the normal function of the nervous system and the gastrointestinal tract. Called also {nicotinic acid} and {antipellagra vitamin}. Chemical formula {C6H5NO2}, chemically it is 3 pyridinecarboxylic… …   The Collaborative International Dictionary of English

  • niacin — (n.) pellagra preventing vitamin in enriched bread, 1942, coined from ni(cotinic) ac(id) + IN (Cf. in) (2), chemical suffix; suggested by the American Medical Association as a more commercially viable name than nicotinic acid. The new name was… …   Etymology dictionary

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  • niacin — nicotinic acid ic o*tin ic ac id, n. (Chem.) An organic acid ({C6H5NO2}), a carboxylated derivative of pyridine, obtained by the oxidation of nicotine; called also {niacin} and {antipellagra vitamin}, and {vitamin B5}. Chemically it is 3… …   The Collaborative International Dictionary of English

  • Niacin — Nicotinic acid, one of the water soluble B vitamins. * * * SYN: nicotinic acid. * * * ni·a·cin nī ə sən n a crystalline acid C6H5NO2 that is a member of the vitamin B complex occurring usu. in the form of a complex of niacinamide in various… …   Medical dictionary

  • niacin — мед. ниацин (niacin)  Водорастворимый витамин.   Высвобождает энергию в тканях и клетках тела.   Способствует укреплению нервной системы и улучшению пищеварения. см. тж витамины …   Универсальный дополнительный практический толковый словарь И. Мостицкого

  • Niacin — PP Faktor; Vitamin B3; Nicotinsäure * * * Ni|a|cin [Kunstw. aus engl. nicotinic acid = Nicotinsäure u. ↑ in (3)], das; s: amer. Freiname für ↑ Nicotinsäure. * * * Niac …   Universal-Lexikon

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