isoniazid

isoniazid
/uy'seuh nuy"euh zid/, n. Pharm.
a white, crystalline, water-soluble solid, C6H7N3O, used in the treatment of tuberculosis.
[1950-55; short for ISONICOTINIC ACID HYDRAZIDE]

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▪ drug

      drug used in the treatment and prevention of tuberculosis. Isoniazid commonly is used in combination with other drugs, such as rifampin, ethambutol, pyrazinamide, or streptomycin; these drugs are used with isoniazid in order to prevent, or at least delay, the development of isoniazid-resistant strains of tuberculin bacilli. Treatment usually is continued for many months. The most important drug in the therapy of tuberculosis, isoniazid was introduced into medicine in 1952; it usually is administered orally, but it can be given by injection. Side effects may include hepatitis (especially in older patients), peripheral neuropathy, dizziness, and headache.

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Universalium. 2010.

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  • Isoniazid — I|so|ni|a|zid [Kurzw. aus Isonicotinsäurehydrazid], das; s: als Nicotinsäure Antimetabolit wirkendes Tuberkulosemittel. * * * Isoniazid   das, s, Tuberkulostatika …   Universal-Lexikon

  • isoniazid — isonicotinic acid hydrazide; = INH; n. a drug used in the treatment of tuberculosis, usually taken by mouth. Because tuberculosis bacteria soon become resistant to isoniazid, it is given in conjunction with other antibiotics. Occasional side… …   The new mediacal dictionary

  • isoniazid neuropathy — polyneuropathy seen in some patients on isoniazid therapy, consisting of symmetrical numbness and paresthesias of the lower extremities …   Medical dictionary

  • isoniazid — noun Etymology: is + nicotinic acid + hydrazide Date: 1952 a crystalline compound C6H7N3O used in treating tuberculosis …   New Collegiate Dictionary

  • isoniazid — noun A medication used in the prevention and treatment of tuberculosis, having the chemical formula CHNO …   Wiktionary

  • Isoniazid — Iso|ni|azi̱d [Kurzwort aus ↑Isonikotinsäurehydrazid] s; [e]s: = Isonikotinsäurehydrazid …   Das Wörterbuch medizinischer Fachausdrücke

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