imipramine

imipramine
/i mip"reuh meen'/, n. Pharm.
a tricyclic antidepressant, C19H24N2, used for the symptomatic relief of depression.
[1955-60; contr. and rearrangement of iminodibenzyl and aminopropyl, components of the chemical name]

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▪ drug
      synthetic drug used in the treatment of depression and enuresis (bed-wetting). Introduced into medicine in the 1960s, imipramine was the first tricyclic antidepressant, a class named for its three-ring molecular structure. Imipramine inhibits reuptake of the neurotransmitters norepinephrine (epinephrine and norepinephrine) and serotonin in the brain. It is usually administered orally but may be given by intramuscular injection. The drug has a wide variety of side effects, which include dryness of the mouth, blurred vision, constipation, difficulty in passing urine, and cardiovascular abnormalities.

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Universalium. 2010.

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Look at other dictionaries:

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  • imipramine pamoate — a tricyclic antidepressant with uses similar to those of imipramine hydrochloride, except that it is not used to treat enuresis …   Medical dictionary

  • imipramine — noun Etymology: imide + propyl + amine Date: 1958 a tricyclic antidepressant drug C19H24N2 …   New Collegiate Dictionary

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  • imipramine — imip·ra·mine im ip rə .mēn n a tricyclic antidepressant drug administered esp. in the form of its hydrochloride C19H24N2·HCl or pamoate (C19H24N2)2·C23H16O6 see TOFRANIL * * * n. a drug administered by mouth or injection to treat depression (see …   Medical dictionary

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