ibogaine

ibogaine
/i boh"geuh een'/, n. Pharm.
an alkaloid, C20H26N2O, obtained from an African shrub, Tabernanthe iboga, having antidepressant and hallucinogenic properties.
[ < F ibogaïne (1901) < NL iboga the shrub's specific epithet (said to be < an indigenous language of the Congo) + F -ine -INE2]

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▪ drug
      hallucinogenic drug and the principal iboga alkaloid, found in the stems, leaves, and especially in the roots of the African shrub Tabernanthe iboga. Ibogaine was isolated from the plant in 1901 and was synthesized in 1966. In small doses it acts as a stimulant. The peoples of West Africa and the Congo region have used iboga extracts or chewed the root of the plant in order to remain calm but alert while stalking game.

      Chemically, ibogaine is an indole hallucinogen that can block the action of serotonin (the indole amine transmitter of nerve impulses) in brain tissue. Ibogaine occurs as a crystalline solid and is soluble in alcohol and other organic solvents. Ibogaine hydrochloride is a crystalline salt, soluble in alcohol and in water. It was proposed for medical use as an antidepressant, but it was rejected in favour of more practical and less toxic drugs.

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Universalium. 2010.

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  • Ibogaine — Ibogaïne Ibogaïne Structure de l ibogaine Général Nom IUPAC 12 Méthoxyibogamine No CAS …   Wikipédia en Français

  • Ibogaïne — Structure de l ibogaine Général Nom IUPAC 12 Méthoxyibogamine No CAS …   Wikipédia en Français

  • ibogaine — (n.) nerve stimulant, 1901, from Fr. ibogaine, from iboga, Congolese name of the shrub from which the chemical is extracted, + chemical suffix INE (Cf. ine) (2) …   Etymology dictionary

  • ibogaine — [ī′bō gā΄ēn΄, ī′bō gā΄in; ī bō′gā ēn΄, i bō′gāēn] n. an alkaloid, C20H26N2O, extracted from a tropical African shrub ( Tabernanthe iboga) of the dogbane family, and acting as an antidepressant or stimulant: may cause hallucinations, paralysis,… …   English World dictionary

  • Ibogaine — drugbox IUPAC name = 12 Methoxyibogamine width = 180 CAS number = 83 74 9 PubChem = 363272 C=20 | H=26 | N=2 | O=1 molecular weight = 310.433 g/mol smiles = CCC1CC2CC3C1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC melting point = 152 melting high = 153… …   Wikipedia

  • ibogaine — noun A naturally occurring psychoactive compound found in a number of plants, principally iboga, and used for medicinal and ritual purposes in African spiritual traditions of the Bwiti …   Wiktionary

  • ibogaine — Indole alkaloid of the iboga group. Obtained from several parts of the African shrub Tabernanthe iboga (family Apocynaceae). Used by African hunters to arrest movement of the hunter; hallucinogenic, antidepressant, and euphoric. * * * ibo·ga·ine… …   Medical dictionary

  • ibogaine — [ɪ bəʊgəˌi:n] noun a hallucinogenic compound from the roots of a West African shrub, sometimes used to treat heroin or cocaine addiction. Origin early 20th cent.: from a blend of iboga (local name for the compound) and cocaine …   English new terms dictionary

  • ibogaine — ibo·ga·ine …   English syllables

  • ibogaine — ə̇ˈbōgəˌēn noun ( s) Etymology: International Scientific Vocabulary iboga (from New Latin, specific epithet of Tabernanthe iboga, from a native name in central Africa) + ine : a crystalline alkaloid hallucinogen C20H26N2O obtained from the roots …   Useful english dictionary

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