hyperkeratotic /huy'peuhr ker'euh tot"ik/, adj.
/huy'peuhr ker'euh toh"sis/, n.
1. Pathol.
a. proliferation of the cells of the cornea.
b. a thickening of the horny layer of the skin.
2. Also called x-disease. Vet. Pathol. a disease of cattle resulting from their physical contact with or eating of objects or food contaminated by wood preservatives or machinery lubricants containing highly chlorinated naphthalenes, characterized by thickening and hardening of the skin, abnormal secretion of tears and saliva, and diarrhea.
[1835-45; < NL; see HYPER-, KERATOSIS]

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also called  X-disease 

      in cattle, a disease characterized by inflammation and thickening of the horny covering of the epidermis, the outermost layer of the skin. Other symptoms include weight loss, wartlike swellings in the mouth, drooling, and a runny nose. Severely afflicted animals usually die. Although once attributed to a virus, the disease is now known to be caused by the ingestion of feed contaminated with chlorinated naphthalene, a lubricant used to grease feed mills. The term hyperkeratosis is also used to describe the hypertrophy of the corneous layer of the human skin.

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Universalium. 2010.

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Look at other dictionaries:

  • hyperkeratosis — [hī΄pər ker΄ə tō′sis] n. pl. hyperkeratoses [hī΄pər ker΄ə tō′sēz΄] [ HYPER + KERATOSIS] 1. an increase in the thickness of the horny layer of the skin 2. an increase of the cells of the cornea of the eye hyperkeratotic [hī΄pər ker΄ətät′ik] adj …   English World dictionary

  • Hyperkeratosis — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 20624 ICD10 = ICD9 = ICD9|701.1 ICDO = OMIM = MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Hyperkeratosis results when an excess of proteins called keratins are produced. In humans …   Wikipedia

  • hyperkeratosis — Thickening of the horny layer of the epidermis or mucous membrane. SEE ALSO: keratoderma, keratosis. SYN: hyperkeratinization. h. congenita SYN: ichthyosis vulgaris. diffuse h. of palms and soles an …   Medical dictionary

  • hyperkeratosis — “+ noun (plural hyperkeratoses) Etymology: New Latin, from hyper + keratosis 1. : hypertrophy of the corneous layer of the skin 2. a. : any of various conditions marked by hyperkeratosis …   Useful english dictionary

  • hyperkeratosis follicularis in cutem penetrans — hyperkeratosis follicularis et parafollicularis in cutem penetrans Kyrle disease …   Medical dictionary

  • hyperkeratosis palmaris et plantaris — palmoplantar hyperkeratosis, hyperkeratosis palmoplantaris, hyperkeratosis of palms and soles see under keratoderma …   Medical dictionary

  • hyperkeratosis — noun (plural hyperkeratoses) Etymology: New Latin Date: 1841 hypertrophy of the corneous layer of the skin • hyperkeratotic adjective …   New Collegiate Dictionary

  • hyperkeratosis — noun Excess keratin formation on the skin surface, as can be seen in a number of dermatologic conditions. See Also: hypokeratosis …   Wiktionary

  • hyperkeratosis — n. abnormal thickening of the skin (Medicine) …   English contemporary dictionary

  • hyperkeratosis — [ˌhʌɪpəkɛrə təʊsɪs] noun Medicine abnormal thickening of the outer layer of the skin …   English new terms dictionary

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