/huy'bri doh"meuh/, n., pl. hybridomas. Biotech.
a hybrid cell made in the laboratory by fusing a normal cell with a cancer cell, usu. a myeloma or lymphoma, in order to combine desired features of each, as the ability of the cancer cell to multiply rapidly with the ability of the normal cell to dictate the production of a specific antibody. Cf. monoclonal antibody.
[1975-80; HYBRID + -OMA]

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Universalium. 2010.

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  • Hybridoma — are cells that have been engineered to produce a desired antibody in large amounts. To produce monoclonal antibodies, B cells are removed from the spleen of an animal that has been challenged with the relevant antigen. These B cells are then… …   Wikipedia

  • hybridoma — hybridoma. См. гибридома. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • hybridoma — [hī΄bri dō′mə] n. [ HYBRID + (MYEL)OMA] a tissue culture consisting of cancer cells fused to lymphocytes to mass produce a specific antibody …   English World dictionary

  • Hybridoma — A cell hybrid resulting from the fusion of a cancer cell and a normal lymphocyte (a type of white blood cell). The hybridoma is immortal in the laboratory and makes the same products as its parent cells forever. * * * A tumor of hybrid cells used …   Medical dictionary

  • Hybridoma — Abb.1: (1) Immunisation einer Maus; (2) Isolation von B Zellen aus der Milz; (3) Kultivierung von Myelomazellen; (4) Fusionierung von B und Myelomzelle; (5) Selektion und Screening geeigneter Zelllinien; (6) Weiterverarbeitung bzw. Aufbewahrung… …   Deutsch Wikipedia

  • hybridoma — noun Date: 1978 a hybrid cell produced by the fusion of an antibody producing lymphocyte with a tumor cell and used to culture continuously a specific monoclonal antibody …   New Collegiate Dictionary

  • hybridoma — (hi brī do mah) A fast growing cell line produced by fusing a cancer cell (myeloma) to another cell, such as an antibody producing cell …   Dictionary of microbiology

  • hybridoma — A cell hybrid in which a tumour cell forms one of the original source cells. In practice, confined to hybrids between T or B lymphocytes and appropriate myeloma cell lines …   Dictionary of molecular biology

  • hybridoma — noun A hybrid cell engineered from a lymphocyte and a tumour cell; used to generate monoclonal antibodies …   Wiktionary

  • hybridoma — hy·bri·do·ma …   English syllables

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