cyclosporine

cyclosporine
/suy'kleuh spawr"een, -in, -spohr"-, sik'leuh-/, n. Pharm.
a substance, synthesized by certain soil fungi, that suppresses the immune response by disabling helper T cells, used to minimize rejection of foreign tissue transplants.
Also, cyclosporin /suy'kleuh spawr"in, -spohr"-, sik'leuh-/.
[1975-80; < NL Cyclospor(eae) a class of brown algae (see CYCLO-, -SPORE, -EAE) + -IN2]

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Universalium. 2010.

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  • cyclosporine — [sī΄klō spôr′ēn, sī΄kləspôr′ēn] n. a drug, produced by a fungus (Tolypocladium inflatum), that suppresses the T cells that reject foreign tissue after an organ transplant without suppressing other cells that fight infections and cancer: also… …   English World dictionary

  • Cyclosporine — Ciclosporine Cyclosporine Général Nom IUPAC [R [[R*,R* (E)]] cyclic(L alanyl D alanyl N methyl L leucyl N methyl L leucyl N methyl L valyl 3 hydroxy N,4 dimethyl L 2 amino 6 octenoyl L α amino butyryl …   Wikipédia en Français

  • cyclosporine — ciclosporine [ siklospɔrin ] n. f. VAR. cyclosporine • cyclosporine 1976; de cyclo et spore ♦ Médicament immunodépresseur utilisé pour éviter les réactions de rejet après une greffe d organe. ● ciclosporine ou cyclosporine nom féminin Médicament… …   Encyclopédie Universelle

  • cyclosporine — cyclosporin cyclosporin, cyclosporine cyclosporine . a chemical substance produced by some soil fungi, which suppresses the cellular immune response by inhibiting T cell activation, and has been used in medicine to reduce foreign tissue rejection …   The Collaborative International Dictionary of English

  • cyclosporine A — ciklosporinas A statusas T sritis chemija apibrėžtis Ciklinis peptidas, imuniteto reguliatorius. atitikmenys: angl. cyclosporine A rus. циклоспорин A …   Chemijos terminų aiškinamasis žodynas

  • cyclosporine-associated arteriopathy — a manifestation of chronic cyclosporine induced nephrotoxicity, consisting of hyaline degeneration of the tunica media and mucoid thickening of the intima of the arterioles of the peripheral vascular tree …   Medical dictionary

  • cyclosporine effect — perimyocytic fibrosis (with interstitial cellular infiltrates) occurring in transplanted hearts, due to the use of cyclosporine …   Medical dictionary

  • cyclosporine — also cyclosporin noun Etymology: International Scientific Vocabulary cycl + spor + 2 ine Date: 1976 an immunosuppressive polypeptide drug C62H111N11O12 obtained from various imperfect fungi and used especially to …   New Collegiate Dictionary

  • cyclosporine — noun a cyclic oligopeptide, obtained from soil fungi, used as an immunosuppressive drug after an organ transplant …   Wiktionary

  • cyclosporine — A cyclic oligopeptide immunosuppressant produced by the fungus Tolypocladium inflatum Gams; used to inhibit organ transplant rejection. SYN: cyclosporin A. * * * cy·clo·spor·ine .sī klə spȯr ən, .ēn n a cyclosporin C62H111N11O …   Medical dictionary

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