Nucleic acid analogues — Not to be confused with degenerate bases. For phosphoramidite synthesis of nucleic acids, see Oligonucleotide synthesis. RNA with its nucleobases to the left and DNA to the right. Nucleic acid analogues are compounds structurally similar (analog) … Wikipedia
Zinc finger nuclease — Zinc finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA binding domain to a DNA cleavage domain. Zinc finger domains can be engineered to target desired DNA sequences and this enables zinc finger… … Wikipedia
Proflavine — (pron. pro fla¢vin ), also called proflavin and diaminoacridine, is an acriflavine derivative, a disinfectant bacteriostatic against many gram positive bacteria. It has been used in the form of the dihydrochloride and hemisulfate salts as a… … Wikipedia
Genetic code — A series of codons in part of a messenger RNA (mRNA) molecule. Each codon consists of three nucleotides, usually representing a single amino acid. The nucleotides are abbreviated with the letters A, U, G and C. This is mRNA, which uses U (uracil) … Wikipedia
Shotgun sequencing — In genetics, shotgun sequencing, also known as shotgun cloning, is a method used for sequencing long DNA strands. It is named by analogy with the rapidly expanding, quasi random firing pattern of a shotgun.Since the chain termination method of… … Wikipedia
Gene expression — For vocabulary, see Glossary of gene expression terms. For a non technical introduction to the topic, see Introduction to genetics. Genes are expressed by being transcribed into RNA, and this transcript may then be translated into protein. Gene… … Wikipedia
Molecular dynamics — (MD) is a computer simulation of physical movements of atoms and molecules. The atoms and molecules are allowed to interact for a period of time, giving a view of the motion of the atoms. In the most common version, the trajectories of molecules… … Wikipedia
DNA polymerase — 3D structure of the DNA binding helix turn helix motifs in human DNA polymerase beta A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their… … Wikipedia
Wobble — or wobbles can mean: * Wobble base pair, a type of basepair in genetics translation * Milankovitch wobble, the change in the axial tilt, axial precession and orbital eccentricity of the earth over long periods * Wobbler disease, also known as… … Wikipedia
Small interfering RNA — (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of 20 25 nucleotide long double stranded RNA molecules that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway … Wikipedia