pen·i·cil·lin·ase (pĕn'ĭ-sĭlʹĭ-nās') n.
Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used in medicine to treat allergic reactions to penicillin. Also called beta-lactamase.

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Universalium. 2010.

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  • pénicillinase — ● pénicillinase nom féminin Enzyme sécrétée par diverses bactéries et capable d inactiver certains antibiotiques du groupe des pénicillines. ⇒PÉNICILLINASE, subst. fém. BIOCHIM. Enzyme produit par certains microbes et qui détruit l action de la… …   Encyclopédie Universelle

  • Penicillinase — Pen i*cil lin*ase, n. (Bioch.) an enzyme which destroys the antibacterial activity of penicillin by hydrolyzing the amide bond in the beta lactam ring. Many penicillinases are known, and are produced by a wide variety of bacteria. The production… …   The Collaborative International Dictionary of English

  • Penicillinase — Penicillase spaltet das Vierring Lactam (β Lactamring) eines Penicillins hydrolytisch. Die entstehende Carbonsäure decarboxyliert anschließend spontan. Penicillinase ist ein von verschiedenen Bakterien produziertes Enzym, welches in der Lage ist …   Deutsch Wikipedia

  • penicillinase — 1. SYN: β lactamase. 2. A purified enzyme preparation obtained from cultures of a strain of Bacillus cereus; formerly used in the treatment of slowly developing or delayed penicillin reactions. Used by bacteria to develop penicillin resistance. * …   Medical dictionary

  • Penicillinase — Pe|ni|cil|li|na|se [↑ Penicillin u. ↑ ase], die; , n: eine β Lactamase, die die Amidbindung der Penicilline spaltet. * * * Penicillinase   die, , von bestimmten Bakterien (u. a. Escherichia coli und einigen Staphylokokkenarten) gebildetes Enzym,… …   Universal-Lexikon

  • penicillinase — n. an enzyme, produced by some bacteria, that is capable of antagonizing the antibacterial action of penicillin and other beta lactam antibiotics. Purified penicillinase may be used to treat reactions to penicillin. It is also used in diagnostic… …   The new mediacal dictionary

  • penicillinase-resistant antibiotic — noun a form of penicillin that is not rendered inactive by penicillinase • Hypernyms: ↑penicillin • Hyponyms: ↑nafcillin, ↑Nafcil, ↑oxacillin …   Useful english dictionary

  • penicillinase — noun Date: 1940 beta lactamase …   New Collegiate Dictionary

  • penicillinase — noun A specific type of beta lactamase showing specificity for penicillins …   Wiktionary

  • Penicillinase — Pe|ni|cil|li|na|se 〈f.; Gen.: ; Pl.: unz.; Biochemie〉 Penicillin abbauendes Enzym, das von einigen Bakterien gebildet wird [Etym.: → Penicillin] …   Lexikalische Deutsches Wörterbuch

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