Known or Suspected Chemical Carcinogens

Known or Suspected Chemical Carcinogens

▪ Table
Known or suspected chemical carcinogens
target organ agents industries tumour type
lung tobacco smoke, arsenic, asbestos, crystalline silica, benzo(a)pyrene, beryllium, bis-chloromethyl ether, 1,3-butadiene, chromium
VI compounds, coal tar and pitch, nickel compounds, soots, mustard gas aluminum production,
coal gasification, coke production, hematite mining, painting squamous cell, large cell, and small cell cancer, adenocarcinoma
pleura asbestos … mesothelioma
oral cavity tobacco smoke, alcoholic beverages, nickel
compounds boot and shoe production, furniture manufacture, isopropyl alcohol production squamous cell cancer
esophagus tobacco smoke, alcoholic beverages … squamous cell cancer
gastric smoked, salted, and
pickled foods rubber adenocarcinoma
colon heterocyclic amines,
asbestos pattern making adenocarcinoma
liver aflatoxin, vinyl chloride, tobacco smoke, alcoholic beverages … hepatocellular carcinoma, hemangiosarcoma
kidney tobacco smoke … renal cell cancer
bladder tobacco smoke, 4-aminobiphenyl,
benzidine, 2-naphthylamine magenta manufacture, auramine manufacture transitional cell cancer
prostate cadmium … adenocarcinoma
skin arsenic, benzo(a)pyrene,
coal tar and pitch, mineral
oils, soots coal gasification, coke production squamous cell cancer, basal cell cancer
bone marrow benzene, tobacco smoke, ethylene oxide,
antineoplastic drugs rubber leukemia
Source: Taken from Vincent T. DeVita, Jr., Samuel Hellman, and Steven A. Rosenberg (eds.), Cancer: Principles & Practice of Oncology (1997).
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