Fröhlich's syndrome

Fröhlich's syndrome

▪ medical disorder
also called  Adiposogenital Dystrophy,  

      rare childhood metabolic disorder characterized by obesity, growth retardation, and retarded development of the genital organs. It is usually associated with tumours of the hypothalamus, causing increased appetite and depressed secretion of gonadotropin. The disease is named for Alfred Fröhlich, the Austrian neurologist who first described its typical pattern.

      The syndrome occurs most frequently in boys and, because of the close association between the pituitary (pituitary gland) and the hypothalamus, may be associated with reduced pituitary function. Impaired vision sometimes results from impingement of the tumour on the optic nerve. Fröhlich's syndrome is treated by removing the tumour and restricting diet until normal weight is achieved.

      Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no endocrine disturbances, however, and they mature normally after delayed puberty.

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Universalium. 2010.

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  • Fröhlich's syndrome — a disorder of the hypothalamus (part of the brain) affecting males: the boy is overweight with sexual development absent and disturbances of sleep and appetite. Medical names: dystrophia adiposogenitalis [Fröhlich (1871–1953), Austrian… …   The new mediacal dictionary

  • fröhlich's syndrome — …   Useful english dictionary

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  • Fröhlich — is a German language surname meaning cheerful . It may refer to:* Abraham Emanuel Fröhlich, German evangelist, theologian and writer * Albrecht Fröhlich, German Jewish mathematician ** Fröhlich Prize, prize of the London Mathematical Society, in… …   Wikipedia

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