Forbes' disease

Forbes' disease

also called  Cori's disease , or  glycogenosis type III 

      rare hereditary disease in which the the metabolic breakdown of glycogen to the simple sugar glucose is incomplete, allowing intermediate compounds to accumulate in the cells of the liver. Affected persons lack the enzyme amylo-1,6-glucosidase, one of several enzymes involved in glycogen breakdown. Children with the disease have enlarged livers (which usually become normal in size by puberty), are generally stunted in growth, have doll-like facial features, and experience muscular weakness. The disease is fairly mild but can cause frequent hypoglycemia (low blood sugar), producing severe convulsions that may lead to mental retardation. Forbes' disease is inherited as an autosomal recessive trait.

* * *


Universalium. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Forbes disease — Forbes disease. См. гликогеноз III типа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Forbes disease — (forbz) [Gilbert Burnett Forbes, American pediatrician, 1915–2003] glycogen storage disease, type III; see under disease …   Medical dictionary

  • Forbes disease — glycogen storage d., type III …   Medical dictionary

  • Disease — Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the… …   Medical dictionary

  • Forbes — Gilbert B., U.S. pediatrician, *1915. See F. disease. A.P., 20th century U.S. physician. See F. Albright syndrome …   Medical dictionary

  • Glycogen storage disease type III — Classification and external resources Micrograph of glycogen storage disease with histologic features consistent with Cori disease. Liver biopsy. H E stain …   Wikipedia

  • glycogen storage disease — Pathol. any of several inherited disorders of glycogen metabolism that result in excess accumulation of glycogen in various organs of the body. Also called glycogenosis /gluy koh jeuh noh sis/. * * * or glycogenosis Any of numerous types of… …   Universalium

  • Glycogen storage disease — Classification and external resources Glycogen ICD 10 E74.0 …   Wikipedia

  • Lyme disease — Classification and external resources Nymphal and adult deer ticks can be carriers of Lyme disease. Nymphs are about the size of a poppy seed. ICD 10 A …   Wikipedia

  • Alzheimer's disease — Alzheimer redirects here. For other uses, see Alzheimer (disambiguation). Alzheimer s disease Classification and external resources …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”