Burkitt lymphoma

Burkitt lymphoma

      a cancer of the lymphatic system that has an especially high incidence in equatorial Africa among children 3 to 16 years of age. The disease is characterized by tumours of the jaw bones and abdomen and is named after Denis Burkitt (Burkitt, Denis Parsons), who mapped its peculiar geographic distribution across Africa in the 1950s.

      The Epstein-Barr virus, which causes infectious mononucleosis, is present in most persons afflicted with Burkitt lymphoma. However, this cancer is occasionally seen in areas of the world where it is not associated with the virus. Burkitt lymphoma occurs more readily in persons who have been weakened by malaria and in persons suffering from AIDS.

      Burkitt lymphoma is a type of non-Hodgkin lymphoma, and research suggests that it is caused by a genetic mutation in which a piece of chromosome 8 is translocated to chromosome 14. Localized tumours respond well to chemotherapy and are curable. Involvement of the central nervous system, however, can lead to a far more serious prognosis.

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Universalium. 2010.

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  • Burkitt lymphoma — Burkitt lymphoma. См. лимфома Беркитта. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Burkitt lymphoma — An aggressive (fast growing) type of B cell non Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of… …   English dictionary of cancer terms

  • Burkitt lymphoma — A type of non Hodgkin lymphoma (NHL) that most often occurs in young people between the ages of 12 and 30, accounting for 40% to 50% of childhood NHL. The disease usually causes a rapidly growing tumor in the abdomen. Up to 90% of these tumors… …   Medical dictionary

  • Burkitt lymphoma — noun see Burkitt s lymphoma …   New Collegiate Dictionary

  • burkitt lymphoma — noun see burkitt s lymphoma …   Useful english dictionary

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  • Lymphoma — This article is about lymphoma in humans. For the disease in dogs, cats, and ferrets, see lymphoma in animals. Lymphoma Classification and external resources Follicular lymphoma replacing a lymph node …   Wikipedia

  • Burkitt, Denis Parsons — ▪ 1994       Irish physician (b. Feb. 28, 1911, Enniskillen, Northern Ireland d. March 23, 1993, England), recognized the significance of varying climatic conditions and eating habits in the incidence of cancer and certain other diseases. His… …   Universalium

  • Burkitt's lymphoma — Bur·kitt s lymphoma .bər kəts also Burkitt lymphoma kət n a malignant lymphoma that affects primarily the upper and lower jaws, orbit, retroperitoneal tissues situated near the pancreas, kidneys, ovaries, testes, thyroid, adrenal glands, heart,… …   Medical dictionary

  • Burkitt's lymphoma — also Burkitt lymphoma noun Etymology: Denis Parsons Burkitt died 1993 British surgeon Date: 1963 a malignant lymphoma that occurs especially in children of central Africa and is associated with Epstein Barr virus …   New Collegiate Dictionary

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