haptoglobin

haptoglobin
haptoglobin [hap′tə glō΄bin]
n.
a blood protein that binds with free hemoglobin in the bloodstream or at a wound when red blood cells decompose or are destroyed abnormally in the circulation

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hap·to·glo·bin (hăpʹtə-glō'bĭn) n.
A plasma protein that is a normal constituent of blood serum and functions in the binding of free hemoglobin in the bloodstream.
  [Greek haptein, to bind, fasten + hemoglobin.]

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      a colourless protein of the α-globulin fraction of human serum (liquid portion of blood plasma after the clotting factor fibrinogen has been removed) that transports hemoglobin freed from destroyed red blood cells to the reticuloendothelial system, where it is broken down. Three common types—numbered 1-1, 2-1, and 2-2—and three uncommon types of haptoglobin are known and are believed to result from combinations among three alleles (forms of genes). The serum haptoglobin level is raised during inflammations and certain other conditions; it is lowered in hemolytic disease and some types of liver disease.

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Universalium. 2010.

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  • haptoglobin — noun Etymology: International Scientific Vocabulary, from Greek haptein + International Scientific Vocabulary hemoglobin Date: 1941 any of several forms of an alpha globulin found in blood serum that can combine with free hemoglobin in the plasma …   New Collegiate Dictionary

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  • haptoglobin — noun A protein in blood plasma that binds free hemoglobin released from erythrocytes and thereby inhibits its oxidative activity …   Wiktionary

  • Haptoglobin — Hap|to|glo|bin [griech. háptein = anbinden, befestigen; ↑ Globin] ein Plasmaprotein (↑ Glykoprotein) mit je zwei α u. β Ketten, MG ca. 100 000–120 000, das Hämoglobin spezif. bindet u. an dessen Abbau beteiligt ist …   Universal-Lexikon

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