glutathione

glutathione
/glooh'teuh thuy"ohn/, n. Biochem.
a crystalline, water-soluble peptide of glutamic acid, cysteine, and glycine, C10H17N3O6S, found in blood and in animal and plant tissues, and important in tissue oxidations and in the activation of some enzymes.
[1920-25; GLUTA(MIC ACID) + THI- + -ONE]

* * *

      a tripeptide (i.e., compound composed of three amino acids), the chemical name of which is γ-l-glutamyl-l-cysteinylglycine. Widely distributed in nature, it has been isolated from yeast, muscle, and liver. Glutathione has a role in the respiration of both mammalian and plant tissues and protects red blood cells against hydrogen peroxide, which is a toxic by-product of many metabolic reactions, by reducing the peroxide to water. It serves as a cofactor for various enzymes; e.g., glyceraldehyde-3-phosphate dehydrogenase, to which it becomes firmly bound.

* * *


Universalium. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Glutathione — Glutathione[1] …   Wikipedia

  • glutathione — [glo͞ot΄ə thī′ōn΄] n. a polypeptide, C10H17O6N3S, containing cysteine, glutamic acid, and glycine and involved, as an antioxidant and coenzyme, in the normal biochemical reactions occurring in plant and animal tissues …   English World dictionary

  • glutathione — The tripeptide g glutamylcysteinylglycine. It contains an unusual peptide linkage between the g carboxyl group of the glutamate side chain and the amine group of cysteine. The concentration of glutathione in animal cells is around 5mM and its… …   Dictionary of molecular biology

  • glutathione — A tripeptide of glycine, l cysteine, and l glutamate, with l glutamate having an isopeptide bond with the amino moiety of l cysteine. G. has a wide variety of roles in a cell; it is the most prevalent non protein thiol. G. disulfide (GSSG)… …   Medical dictionary

  • glutathione — n. a peptide containing the amino acids glutamic acid, cysteine, and glycine. It functions as a coenzyme in several oxidation reduction reactions. Glutathione serves as an antioxidant: it reacts with potentially harmful oxidizing agents and is… …   The new mediacal dictionary

  • Glutathione synthetase deficiency — Classification and external resources Glutathione OMIM 266130 …   Wikipedia

  • Glutathione reductase — Glutathione reductase, also known as GSR, is a human gene.cite web | title = Entrez Gene: GSR glutathione reductase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=2936| accessdate = ] The protein encoded… …   Wikipedia

  • Glutathione disulfide — IUPAC name (2S) 2 amino 5 [[(2R) 3 [(2R) 2 [[(4S) 4 amino 5 hydroxy 5 oxopent …   Wikipedia

  • Glutathione dehydrogenase (ascorbate) — Identifiers EC number 1.8.5.1 CAS number 9026 38 4 …   Wikipedia

  • Glutathione S-transferase Mu 1 — (gene name GSTM1) is a human glutathione S transferase. PBB Summary section title = summary text = Cytosolic and membrane bound forms of glutathione S transferase are encoded by two distinct supergene families. At present, eight distinct classes… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”