glanders

glanders
—glanderous, adj.
/glan"deuhrz/, n. (used with a sing. v.) Vet. Pathol.
a contagious disease chiefly of horses and mules but communicable to humans, caused by the bacterium Pseudomonas mallei and characterized by swellings beneath the jaw and a profuse mucous discharge from the nostrils. Cf. farcy.
[1475-85; < MF glandres swollen glands < L glandulae swollen glands, lit., little acorns. See GLAND1, -ULE]

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also called  Farcy,  

      specific infectious and contagious disease of solipeds (the horse, ass, and mule); secondarily, humans may become infected through contact with diseased animals or by inoculation while handling diseased tissues and making laboratory cultures of the causal bacillus. In 1882 the bacteriologists Friedrich Löffler and Wilhelm Schütz in Germany isolated and identified the causal agent, which they named the Bacillus mallei, now designated technically as the Pfeifferella mallei or Malleomyces mallei. After infection, the disease usually follows a chronic course with a variable period of incubation extending from several weeks to several months.

      Clinical cases in solipeds are manifested by a chronic nasal discharge from one or both nostrils, with or without visible ulceration of the nasal septum; chronic enlargement and hardening of the submaxillary lymph glands without outward discharge of pus; or the presence of pustules and ulcers (farcy buds) on the skin of the hindlegs or other parts of the body. Nonclinical, or latent, cases are essentially pulmonary in type, and the lesions remain in a concealed state (occult) in the lungs as tubercle-like nodules and suppurating foci. In many latent cases, the affected animal shows slight signs of lung trouble (altered breathing).

      The only effective policy for the control of the disease is slaughter of infected animals and proper cleaning and disinfection of the affected premises. Under this policy, glanders was almost completely eradicated in the U.S., Great Britain, and Canada. The disease is still known to prevail in some parts of Europe, Asia, and Africa.

      Glanders in man most frequently occurs through occupational contact with diseased horses, from making an autopsy on a diseased animal, or from making laboratory cultures of the bacteria. The treatment of human glanders has included the use of many drugs, largely tonic and palliative, combined with surgical treatment. In selected cases, the use of certain antibiotics has shown promising results.

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Universalium. 2010.

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Look at other dictionaries:

  • Glanders — Classification and external resources ICD 10 A24.0 ICD 9 024 …   Wikipedia

  • Glanders — Glan ders, n. [From {Gland}.] (Far.) A highly contagious and very destructive disease of horses, asses, mules, etc., characterized by a constant discharge of sticky matter from the nose, and an enlargement and induration of the glands beneath and …   The Collaborative International Dictionary of English

  • glanders — horse disease characterized by glandular swelling, early 15c., from O.Fr. glandres swollen glands, pl. of glandre, from L. glandula (see GLAND (Cf. gland)) …   Etymology dictionary

  • glanders — [glan′dərz] n. [OFr glandres < L glandulae, swollen glands in the neck, pl. of glandula: see GLAND1] a contagious, chronic or acute disease of horses, mules, etc. characterized by fever, swollen lymph nodes, ulcerous nodules on the skin,… …   English World dictionary

  • Glanders — Apparently recorded in the surviving registers of England since the 18th century and in the spellings of Gland, Glander, Glanders, Glendor, Glend, Glind and Glinds, we believe that the origin may be Anglo Saxon. The surname would seem to… …   Surnames reference

  • glanders pneumonia — pneumonia associated with glanders, characterized by caseous or calcified granules and pulmonary consolidation; seen in both humans and horses. Called also p. malleosa …   Medical dictionary

  • glanders — noun plural but singular or plural in construction Etymology: Middle French glandre glandular swelling on the neck, from Latin glandulae, from plural of glandula, diminutive of gland , glans Date: 1523 a contagious and destructive disease… …   New Collegiate Dictionary

  • glanders — noun An infectious disease of horses, mules and donkeys caused by the bacterium Burkholderia, one species of which may be transmitted to humans …   Wiktionary

  • glanders — A chronic debilitating disease of horses and other equids, as well as some members of the cat family, caused by Pseudomonas mallei and transmissible to humans. It attacks the mucous membranes of the nostrils of the horse, producing an increased… …   Medical dictionary

  • glanders — glan·ders || glændÉ™(r)z n. infectious disease of horses and mules …   English contemporary dictionary

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